On July 31, 1784, Denis Diderot passed away in Paris and with him, the memory of the biggest editorial epic of the Age of Enlightenment: the Encyclopedia, or a Systematic Dictionary of the Sciences, Arts and Crafts. This monumental work of art is the result of the fight of a man against obscurantism and of his unfailing trust in reason. Carried by men such as Voltaire or Rousseau, the adventure will last 25 years. It will encounter numerous unforeseen developments and end in clandestinity but will not fail to revolutionize the publishing world.